It is defined as three or more consecutive pregnancy losses before 20 weeks of gestation. Habitual abortion may occur due to multiple factors.
updated on:2025-01-20 08:10:24
Habitual abortion is recurring spontaneous abortion in women and it affects 1% of couples trying to conceive. It is defined as three or more consecutive pregnancy losses before 20 weeks of gestation.
The exact cause of it remains unexplained in 50% of the cases of habitual abortion.
Common causes of habitual abortion include:
1)
Uterine
abnormalities or defective structure of the uterus
15-20%
from mullerian fusion defects.
2)
Infections
Chlamydia, bacterial infections, TORCH [
toxoplasma, rubella, cytomegalovirus, herpes ] infections
3)
Genes
Both parental and embryonic defects are
responsible.
4)
Endocrine
or hormonal
Luteal phase defect [ problem with corpus luteal progesterone hormone production for maintaining pregnancy] , insulin
dependent diabetes mellitus, thyroid disorders
5)
Metabolic
Folate and vitamin B12
deficiency and[ hyperhomocysteinaemia ]raised levels of homocysteine in the
blood due to the deficiency cause abortion.
6)
Immunologic
The exact role of immunological
factors is still not clear, however they play some role in causing miscarriage
in a fraction of pregnant women.
7)
Environmental
Alcohol
consumption, smoking, high caffeine.
8] Thrombophilic
Thrombosis or clot formation in uteroplacental blood vessels such as
anti-phospholipid antibody syndrome is another cause of habitual abortion.
Diagnosis of habitual abortion
Tests
a. For the diagnosis
of uterine defects following tests are done:
·
Hysteroscopy
·
Hysterosalpingography
(HSG)
·
Sono hysterograms
·
Vaginal
ultrasonography
All these
tests can help to visualize uterine abnormalities.
B. antiphospholipid syndrome
[APS]
Diagnosis of APS requires the presence of at
least 1 of the clinical criteria and at least 1 of the laboratory criteria. The
clinical criteria include the following:
·
Vascular
thrombosis or occlusion by clots.
·
3 or
more consecutive unexplained miscarriages.
·
At
least 1 unexplained death of a morphologically normal fetus at or after 10
weeks' gestation
· At least 1 premature birth of a morphologically normal neonate at or before 34 weeks' gestation, associated with severe preeclampsia or severe placental insufficiency.
·
The
laboratory criteria include the following:
·
aCL:
Immunoglobulin G (IgG) and/or immunoglobulin M (IgM) isotype is present in
medium or high titer on 2 or more occasions, 6 or more weeks apart.
·
Prolonged
phospholipid-dependent coagulation on screening tests.
·
Inability
to correct the prolonged screening test with normal platelet-poor plasma.
·
Successful
correction of the prolonged screening test with excess phospholipids.
·
Exclusion
of other coagulopathies as clinically indicated and heparin.
C.
Other tests for diagnosing habitual
abortion
·
Fasting
and random blood glucose level
·
Thyroid
function test & antithyroid antibodies
·
Female
sex hormones
Treatment for habitual abortion
·
Addressing
the causes of habitual abortion is the appropriate mode of treatment to be
adopted.
·
If
hormonal problems cause habitual abortion hormone replacement therapy may be required
much before planning a pregnancy.
·
Manage
luteal phase defect with progesterone supplementation.
·
Manage
diabetes in women with high blood glucose level.
·
Uterine
abnormalities are to be rectified by surgical repair
·
Treat infections
with appropriate medications.
·
Avoid
alcohol consumption, smoking.
·
Stress
management
· As advanced maternal age is a risk advise to the couple to plan pregnancy at a younger age before mid-thirties.
Homeopathy for treating habitual abortion:
Caulophyllum, ferrum,kali-carb,helonius,plumbum,sabina,sepia,
sulphur, viburnum,zinc are some of the important homeopathic medications to
prevent habitual abortion.
Written by dr sanjana vb [ copyright]
References
2. https://emedicine.medscape.com/article/260495-overview?form=fpf
3. Homeopathic medical repertory
Reproductive health include health of a female body and mind from beginning of menstruation at puberty [menarche] to menopause. A healthy nutritious diet is very important during reproductive years or even while planning pregnancy and at menopause. Beyond nutrition reproductive health includes various other factors also which are discussed below.
It is defined as three or more consecutive pregnancy losses before 20 weeks of gestation. Habitual abortion may occur due to multiple factors.
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